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Search Results for " lpa1 antagonist 1 "

10

Compounds

Cat No. Product Name Synonyms Targets
T15785 LPA1 receptor antagonist 1 LPA1 R antagonist 1 LPA Receptor
LPA1 receptor antagonist 1(LPA1 R antagonist 1) is a selective and potent lysophosphatidic acid (LPA1) receptor antagonist (IC50 : 25 nM) for the study of idiopathic pulmonary fibrosis.
T7689 Tetradecyl Phosphonate LPA Receptor
Tetradecyl phosphonate is a pan-antagonist of lysophosphatidic acid 1 (LPA1), LPA2, and LPA3 receptors.
T39647 BMS-986278 LPA Receptor
BMS-986278 is an orally active and potent hemophosphatidic acid receptor 1 (LPA1) antagonist with Kb values of 6.9 nM and 4.0 nM for human and mouse LPA1, respectively.BMS-986278 may be investigated for use in idiopathic...
T7393 ONO-7300243 LPA Receptor , LPL Receptor
ONO-7300243 is an antagonist of lysophosphatidic acid receptor 1 (LPA1; IC50 : 0.16 µM).
T4016 BMS-986020 AM152,BMS986020 LPA Receptor , LPL Receptor
BMS-986020 (AM152) is a selective antagonist of LPA1.
T14335 ASP6432 LPA Receptor
ASP6432 is an antagonist of type 1 lysophosphatidic acid receptor (LPA1). For human LPA1 and rat LPA1, the IC50s are 11 nM and 30 nM , respectively.
T29109 VPC12249 VPC-12249,VPC 12249
VPC12249, a lysophosphatidic acid receptor type 1 (LPA1) antagonist, plays a functional role in osteoclast differentiation and bone resorption activity.
T63645 ONO-9780307
ONO-9780307 is a specific antagonist of LPA1 (lysophosphatidic acid receptor 1) (IC50: 2.7 nM).
T28245 ONO-0300302 ONO 0300302
ONO-0300302 is a slow tight binding LPA1 antagonist (IC50: 0.16 nM) used to treat Benign Prostatic Hyperplasia. ONO-0300302 inhibits significantly an LPA-induced increase of intraurethral pressure (IUP) in rat (3 mg/kg, ...
T63439 BMS-986020 sodium
BMS-986020 sodium is a high-affinity lysophosphatidic acid receptor 1 (LPA1) antagonist that inhibits bile acids and phospholipid transport proteins, and inhibits BSEP (IC50: 4.8 μM), MRP4 (IC50: 6.2 μM) and MDR3 (IC50: ...
TargetMol